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Index > Protein center > SLC14A1(Gene name) > Human
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  • SLC14A1 (Gene name),
  • Urea transporter 1 (Protein name ),  UT1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    SLC14A1(HUT11;JK;RACH1;UT1;UTE);
    Protein name:
    Urea transporter 1;
    Alternative:
    Urea transporter, erythrocyte;Solute carrier family 14 member 1;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Specialized low-affinity urea transporter. Mediates urea transport in erythrocytes.
    Subcellular Location:
    Membrane Multi-pass membrane protein Cell membrane
    Protein Attributes:
    Sequence length:
    389
    Sequence:
    50:
    MEDSPTMVRV | DSPTMVRGEN | QVSPCQGRRC | FPKALGYVTG | DMKELANQLK | 
    100:
    DKPVVLQFID | WILRGISQVV | FVNNPVSGIL | ILVGLLVQNP | WWALTGWLGT | 
    150:
    VVSTLMALLL | SQDRSLIASG | LYGYNATLVG | VLMAVFSDKG | DYFWWLLLPV | 
    200:
    CAMSMTCPIF | SSALNSMLSK | WDLPVFTLPF | NMALSMYLSA | TGHYNPFFPA | 
    250:
    KLVIPITTAP | NISWSDLSAL | ELLKSIPVGV | GQIYGCDNPW | TGGIFLGAIL | 
    300:
    LSSPLMCLHA | AIGSLLGIAA | GLSLSAPFED | IYFGLWGFNS | SLACIAMGGM | 
    350:
    FMALTWQTHL | LALGCALFTA | YLGVGMANFM | AEVGLPACTW | PFCLATLLFL | 
    389:
    IMTTKNSNIY | KMPLSKVTYP | EENRIFYLQA | KKRMVESPL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    MIM:
    KEGG:
    SMR:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Urea transporter 1
    MSDS:
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    ELISA Kit for Human Urea transporter 1
    Cat.:
    E12521m
    Price:
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human Urea transporter 1
    Cat.:
    E12521r
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human Urea transporter 1
    Cat.:
    E12521h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    CLIA Kit for Human Urea transporter 1
    Cat.:
    U12521h
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Urea transporter 1
    Cat.:
    U12521m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Urea transporter 1
    Cat.:
    U12521r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Urea transporter 1
    MSDS:
    Please sign in first.
    Polyclonal Antibody for Human Urea transporter 1
    Polyclonal Antibody for Human Urea transporter 1
    Polyclonal Antibody for Human Urea transporter 1
    Cat.:
    P12521Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Urea transporter 1
    Monoclonal Antibody for Human Urea transporter 1
    Monoclonal Antibody for Human Urea transporter 1
    Monoclonal Antibody for Human Urea transporter 1
    Monoclonal Antibody for Human Urea transporter 1
    Protein for Human Urea transporter 1
    Protein for Human Urea transporter 1
    Protein for Human Urea transporter 1
    Protein for Human Urea transporter 1

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    Linearity
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    References
    1. 1.
      "Cloning and functional expression of a urea transporter from human bone marrow cells."
      Olives B. , Neau P. , Bailly P. , Hediger M.A. , Rousselet G. , Cartron J.-P. , Ripoche P.
      J. Biol. Chem.269:31649-31652(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT LYS-44
      tissue: Bone marrow.
    2. 2.
      "RACH2, a novel human gene that complements a fission yeast cell cycle checkpoint mutation."
      Davey S. , Beach D.
      Mol. Biol. Cell6:1411-1421(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    3. 3.
      "The molecular basis of the Kidd blood group polymorphism and its lack of association with type 1 diabetes susceptibility."
      Olives B. , Merriman M. , Bailly P. , Bain S. , Barnett A. , Todd T. , Cartron J.-P. , Merriman T.
      Hum. Mol. Genet.6:1017-1020(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);POLYMORPHISM;VARIANT JK(B) ASN-280
    4. 4.
      "At physiological expression levels, the Kidd blood group/urea transporter protein is not a water channel."
      Sidoux-Walter F. , Lucien N. , Olives B. , Gobin R. , Rousselet G. , Kamsteeg E.J. , Ripoche P. , Deen P.M.T. , Cartron J.-P. , Bailly P.
      J. Biol. Chem.274:30228-30235(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Blood.
    5. 5.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2);VARIANT LYS-44
      tissue: Artery smooth muscle.
      tissue: Brain cortex.
      tissue: Caudate nucleus.
    6. 6.
      SeattleSNPs variation discovery resource
      Submitted (2005-02) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS LYS-44 AND ASN-280
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANTS VAL-167 AND ASN-280
      tissue: Colon.
    8. 8.
      "Missense mutations that result in serological JKnull phenotypes."
      Posadas J.B. , Shnyreva M. , Gaur P. , Nakaya S. , Devanaboina M. , Teramura G. , Haile A. , Gaur L.K.
      Submitted (2009-08) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-381;VARIANT ASN-280
    9. 9.
      "Erythroid urea transporter deficiency due to novel JKnull alleles."
      Wester E.S. , Johnson S.T. , Copeland T. , Malde R. , Lee E. , Storry J.R. , Olsson M.L.
      Transfusion48:365-372(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 52-113; 222-257 AND 317-332;VARIANT JK(NULL) MET-319
    10. 10.
      "Stomatin interacts with GLUT1/SLC2A1, band 3/SLC4A1, and aquaporin-1 in human erythrocyte membrane domains."
      Rungaldier S. , Oberwagner W. , Salzer U. , Csaszar E. , Prohaska R.
      Biochim. Biophys. Acta1828:956-966(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;TISSUE SPECIFICITY;IDENTIFICATION IN A COMPLEX WITH STOM;SUBUNIT
    11. 11.
      "Molecular heterogeneity of the Jk(null) phenotype: expression analysis of the Jk(S291P) mutation found in Finns."
      Sidoux-Walter F. , Lucien N. , Nissinen R. , Sistonen P. , Henry S. , Moulds J. , Cartron J.-P. , Bailly P.
      Blood96:1566-1573(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT JK(NULL) PRO-291
    12. 12.
      "Genomic characterization of the Kidd blood group gene: different molecular basis of the Jk(a-b-) phenotype in Polynesians and Finns."
      Irshaid N.M. , Henry S.M. , Olsson M.L.
      Transfusion40:69-74(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT JK(NULL) PRO-291
    13. 13.
      "Two novel Jk(null) alleles derived from 222C>A in Exon 5 and 896G>A in Exon 9 of the JK gene."
      Liu H.M. , Lin J.S. , Chen P.S. , Lyou J.Y. , Chen Y.J. , Tzeng C.H.
      Transfusion49:259-264(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS JK(NULL) LYS-74; VAL-167 AND GLU-299
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